Satluj river is a tributary of Indus River and is one of the longest river that flows through Punjab. Domestic wastes, municipal sewage, industrial effluents, agricultural run-off etc. influences the water quality of river directly or indirectly. This study was carried out at Wajipur Kalan, Ludhiana, a Point of confluence of Bud-dha Nalawhich drains intoSatluj riverafter passing throughhighly populatedLudhianaofstate Punjab during May, 2015 to April, 2016. For this study important water quality parameters such as pH, Electrical Conductivity (EC), Turbidity, Total Alkalinity, Chlorides, Phosphate, Nitrate, Total Hardness, Calcium & Magnesium Hardness, Sodium, Potassium, Iron, Chemical Oxygen Demand (COD), Biological Oxygen Demand (BOD),Dissolved Carbon Dioxide and Heavy metals such as Copper, Cadmium, Chromium, Manganese, Nickel, Zinc and Mercury were ana-lyzed. The analyses were carried out according to APHA, 2012 procedures. The results of the analysis shows that some of the parameters under investigation such as Turbidity, Phosphate, Sodium, COD, BOD, Cadmium and Chromium were beyond the permissible limits prescribed by Bureau of Indian Standards (BIS), 2012 and World Health Organization (WHO), 2011.