Drug Utilization Study of Antihypertensive Medication in Both Sex and Different Age Group attending at Medicine Outpatient Department of a Tertiary Care Hospital

Author(s): Abhijit Das, Sahin Parvin, Avijit Ganguly, Saswati Sarkar, Milan Chakraborty

To observe prescription pattern of different drugs in different age & sex groups with or without comorbidities with the aim of formulating local guidelines in the management of Hypertension in future. Over the period of nine months hypertensive subjects of all age groups were observed attending Medicine Outpatient Department (OPD) of R. G. Kar Medical College & Hospital, Kolkata. Many of whom have comorbidities like coronary artery disease, heart failure, diabetes, dyslipidaemia, bronchial asthma, COPD etc. Pregnant and hypertension due to secondary causes were excluded. Name of the prescribed antihypertensive drug(s).their dose and duration of treatment were noted. Among 250 subjects 115(46%) were male & 135(54%) female. Among all subjects 80(32%) were less than 40yr group, 129 patients (51.6%) are middle aged (40-60 yrs.). Seventy two percent (180) patients were on monotherapy and rest on multiple drugs. Amlodipine was found to be the most preferred agent of monotherapy (43 or 17.2%). One hundred and twenty three patients were with some co-morbidities. As per BHS/NICE guideline, 2011 ACEI/ARB’s should be used much more than any other anti-hypertensive, but here Amlodipine was used much more. The scope of multi drug therapy is actually higher as per the guideline but, here the use of multidrug therapy is less than that recommended.


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